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What is Leqvio?

Leqvio (inclisiran) is an injectable prescription medicine used along with diet and other lipid-lowering medicines in adults who need additional lowering of “bad” cholesterol (LDL-C) and have known cardiovascular disease and/or heterozygous familial hypercholesterolemia (HeFH), an inherited condition that causes high levels of LDL-C. It is not known if Leqvio can decrease problems related to high cholesterol, such as heart attacks or stroke.

How does Leqvio Work?

The liver plays a key role in clearing bad cholesterol (LDL-C) from the blood, but certain proteins in the liver can interfere with this process. Leqvio uses the body's natural processes to prevent many of these proteins from forming in the first place. Leqvio is the first and only small interfering RNA (siRNA) therapy to lower low-density lipoprotein cholesterol (LDL-C).

Leqvio is an injection given by a health care provider with an initial dose, again at 3 months, and then once every 6 months.