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What is Truxima?

Truxima (rituximab-abbs) is a prescription medication used in adults to treat rheumatoid arthritis (RA). It is an antibody which belongs to a class of medications known as biologics (complex medicines produced from living cells). 


Truxima is used for the treatment of adults with rheumatoid arthritis (RA) who were not helped enough by at least one other medicine called a tumor necrosis factor (TNF) antagonist. It is given along with another prescription medicine called methotrexate and is approved to help reduce the signs and symptoms of moderate to severe rheumatoid arthritis (RA). 


How Does Truxima Work? 

Truxima targets a type of white blood cell called a B cell. B cells are part of the immune system and help the body fight off infection. In rheumatoid arthritis (RA), B cells don’t work properly and attack healthy tissue. This causes inflammation in the joints that results in joint pain, swelling, and damage. Truxima may help decrease the number of B cells that are attacking healthy tissue, which could help stop disease progression and joint damage. 

It is administered by intravenous (IV) infusion in a doctor’s office.